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CLASSIC TECHNOLOGY PLATFORM

Widely used for local and systemic nasal drug delivery with extensive range of closures, actuators and accessories available make this spray pump highly adaptable to fit customers’ specific requirements.

 

Key Features
• Excellent spray performance (droplet size distribution – spray pattern)
• Classic is available with optional dose counter
• Ideal for liquid solutions, suspensions, viscous drug formulations including gels

 

Product Characteristics
• Wide range of dose volumes: 45 µl to 140 µl
• Built-in pre-compression provides a fine and reproducible spray
• Fast priming pump with low actuation force
• Available in crimp-on, screw-on and snap-on closures

 

THERAPIES
Allergic Rhinitis / Pain / Central Nervous System / Other Therapies

VP3 TECHNOLOGY PLATFORM

Widely used multidose spray pump worldwide for local and systemic pharmaceutical applications. The industry’s gold standard spray pump for more than 30 years used by many blockbuster prescription drug products marketed worldwide including Asia, Europe, Latin America and the U.S.A.

 

Key Features
• Excellent dose accuracy with a wide range of viscosities
• Materials used can be customized to meet specific formulation needs
• Suitable for liquid solutions, suspensions, viscous formulations including gels

 

Product Characteristics
• Wide range of dose volumes: 50 µl to 140 µl
• Fast priming pump with low actuation force
• Built-in pre-compression provides a fine and reproducible spray
• Available in crimp-on and screw-on closures

 

THERAPIES
Allergic Rhinitis / Other Therapies

VP7 TECHNOLOGY PLATFORM

Designed for the Pharmaceutical industry’s prescriptive nasal sprays, the VP7 are being used by many renowned prescription drug products worldwide.

 

Key Features
• Highly-efficient pre-compression nasal spray pump provides dose regularity and consistent spray
• Preferred platform for electronic add-ons
• Suitable for liquid solutions, suspensions and viscous drug formulations

 

Product Characteristics
• Wide range of dose volumes: 25 µl to 130 µl
• All plastic material made from pharmaceutical grade polyolefin (PP/PE)
• Fast priming pump with low actuation force
• Available in crimp-on, screw-on and snap-on closures
• Wide range of actuators available off-the-shelf

 

THERAPIES (Rx)
Allergic Rhinitis / Pain / Central Nervous System / Other Therapies

CPS (CARTRIDGE PUMP SYSTEM)

A highly versatile spray pump designed for multi-dose delivery of preserved or non-preserved drug formulations. It can be used for a range of other applications which include intra-nasal mass vaccination.

 

Key Features
• Anti-clogging tip seal technology to minimize crystallization with high-viscosity and high-volatile

  formulations
• Proven CPS filter technology allows only sterile air to enter the container
• Fully validated and tested microbiological integrity of preservative-free drug formulations
• Metal-free fluid pathway

 

Product Characteristics
• Wide range of dose volumes: 50 µl to 140 µl
• No anti-microbial additives within the pump components
• Can be sterilized by irradiation
• Gentle alternative to injection for intra-nasal mass vaccination applications; optional one-shot mass

   vaccination cap available

 

THERAPIES (Rx)
Allergic Rhinitis / Pain / Central Nervous System / Vaccines / Other Therapies

EQUADEL®

An unique patient-independent nasal spray pump with no significant variations are observed in dose and spray performance with different patient actuation profiles. It also responds to FDA guidance on partial metering of the drug product, where delivery of an incomplete dose leads to sub-dosing, which the patient may not notice.

 

Key Features
• Patient-independent performance with full dose delivery
• Handles like a conventional spray pump and needs no training
• Suitable for liquid solutions, suspensions and viscous drug formulations

 

Product Characteristics
• Complies with FDA guidance on partial metering
• Wide range of dose volumes: 50 µl to 120 µl
• Unique shot-weight reproducibility
• Fast priming and sharp tail-off with low actuation force
• Screw-on, crimp-on and snap-on closures available
• Can be used with existing actuators

 

THERAPIES (Rx)
Allergic Rhinitis / Pain / Central Nervous System / Other Therapies

UDS (UNIT-DOSE SYSTEM)

These are applicable for therapies where a small and very precise amount of active drug formulation is required in a single nasal or sub-lingual shot.

 

Key Features
• Accurate one shot drug delivery

• Once handed actuation, can be used in any position
• Suitable for liquid and powder drug delivery

 

Product Characteristics
• Liquid dose volumes of 100 µl
• Powder dosage – maximum filling volume 140 mm3
• Drug product and delivery device protected before use
• Patient-independent performance for UDS Powder
• Convenient, ready-to-use primless devices

• Conventional filling techniques

 

THERAPIES (Rx)
Allergic Rhinitis / Pain / Central Nervous System / Vaccines / Other Therapies

BDS (BIO-DOSE SYSTEM)

These are applicable for therapies where a very precise amount of active drug formulation that exceeds 100 µl is required. BDS deliver two nasal or sub-lingual shots; or two half-doses when used for intr-nasal vaccination.

 

Key Features
• Accurate two shot drug delivery

• Once handed actuation, can be used in any position
• Suitable for liquid and powder drug delivery

 

Product Characteristics
• Liquid dose volumes of twice 100 µl
• Powder dosage – maximum filling volume 190 mm3 per chamber
• Drug product and delivery device protected before use
• Convenient, ready-to-use primless devices
• Conventional filling techniques

 

THERAPIES (Rx)
Allergic Rhinitis / Pain / Central Nervous System / Vaccines / Other Therapies

Pro-Ject®

Pro-Ject® is a novel high performance disposable auto-injector designed and developed with patients and healthcare professionals for optimal patient convenience and compliance.

 

Key Features

  • Intuitive, 2 simple handling operations
  • Large and clearly visible control window
  • Safety features (needle is permanently hidden and protected)

 

Key Differentiators

  • Unique audible & 360° visual feedbacks
  • Compact size and/or tailored to specific needs (therapies)

 

For more information:

Get more information about Pro-Ject®

 

VIDEO CLIPLINK

DF30 TECHNOLOGY PLATFORM

The industry gold standard for HFA PMDIS more than 20 years and continuously being a choice for many renowned prescription drug products worldwide.

 

Key Features
• Robust design guarantees accurate and consistent dosage
• A range of valve configurations suitable for various solution and suspension based formulations 
• Suitable for high and low powder loading

 

Product Characteristics
• Wide range of metering volumes: 25 µl to 75 µl
• Optimized retention channel designs to prevent drain back (Loss of Prime)
• New optimized DF30Plus valve for improved functional and pharmaceutical performance and

  compatibility across a wider range of formulations

  

Elastomer Seals
• Seals available in Nitrile, EPDM and Thermolastics Elastomer (TPE)

• Excellent sealing properties and high mechanical strength
• Chemically inert with low water vapour permeability

• Ultra low extractable for excellent compatibility with HFA formulations, patient safety and regulatory

  compliance
• Designed, developed and manufactured by in-house Elastomer Centre

 

THERAPIES (Rx)
Allergic Rhinitis / Asthma & COPD / Other Therapies

Twister®

The versatile affordable dry powder inhaler

 

Key Benefits

  • Simple, Intuitive, easy-to-teach and easy-to-clean
  • Designed for size 3 capsules
  • Functions with both HPMC & Gelatin capsule material
  • Diverse filling range between [5-30mg]
  • Proven efficacy with most currently inhaled powder formulations

 

Key Differentiators

  • Transparency of the dispersion chamber – Simple visual feed-back
  • Rotation and rattling of the capsule during inhalation – Characteristic audible feed-back of dose taken
  • Capsule opening technology (with the 2 capsule parts inside) 
LANDMARK® DOSE INDICATOR

Designed to be easy to use with all metering valves. The Landmark® also helps improve patient compliance while remaining cost effective.

 

A color-coded numeric display is triggered by the mechanical counting device integrated into the actuator.

 

Key Features
• Mechanical dose counting device with only 4 components
• Easy-to-read color-coded numeric display
• Compatible with all types of pMDI actuators including nasal pMDIs

 

Product Characteristics
• Integrated into pMDI actuator
• Suitable for inhalers dispensing up to 200 doses
• Counts downward from lable claim
• Color coding for low dose warning and clear end of use indication

• Eliminates risk of under-counting by design
• Displacement-based counting mechanism is independent of actuation force
• Mechanism does not interfere with airflow path
• Color, shape and fit to actuator are all customizable

 

THERAPIES (Rx)
Allergic Rhinitis / Asthma & COPD / Other Therapies

PROHALER®

A novel high performance pre-metered multi-dose DPI designed for optimal patient compliance.

 

Key Features

  • Unique breath-triggered dose-opening function
  • Patient-friendly design, with 3 simple steps to operate: Open, Breathe In, Close (OBIC)
  • Powerful dispersion engine generates high and consistent performance
  • User feedback of dose taken with highly legible visual dose counter and audible click

 

Product Characteristics

  • Contains 30 individual doses in separate sealed blisters for optimal moisture protection
  • Minimal dependence of product performance on airflow
  • Patient-preferred style
  • Filled on industry standard high speed filling equipment
eDEVICES
Turning high performance drug delivery devices into smart devices
 
Using electronic technology to help patient compliance in the treatment of chronic diseases, we have developed 2 innovative smart solutions, known as eDevices, for pMDIs and spray devices for nasal and sub-lingual applications.
 

e-Dose Counter Platform

  • Meets regulatory recommendations for nasal and sub-lingual spray delivery of controlled substances used in breakthrough pain management
  • Large and highly visible counting display, suitable for patients of all conditions and ages

 

e-Lockout Platform

  • Locking system which prevents overdosing is recommended by regulators for nasal and sub-lingual spray delivery of controlled substances used in breakthrough pain management
  • Prevents the device from being used for a period of time after a pre-defined number of actuations
  • Could be used, for example, to prevent an overdose of potent controlled substances being taken accidentally, or these substances being misused